منابع مشابه
Monitoring Spiking Activity of Many Individual Neurons in Invertebrate Ganglia.
Optical recording with fast voltage sensitive dyes makes it possible, in suitable preparations, to simultaneously monitor the action potentials of large numbers of individual neurons. Here we describe methods for doing this, including considerations of different dyes and imaging systems, methods for correlating the optical signals with their source neurons, procedures for getting good signals, ...
متن کاملReticuline exposure to invertebrate ganglia increases endogenous morphine levels.
OBJECTIVES Given the presence of morphine, its metabolites and precursors in mammalian and invertebrate tissues, it became important to determine if exposing tissues to an opiate alkaloid precursor, reticuline, would result in increasing endogenous morphine levels. METHOD Endogenous morphine levels were determined by high pressure liquid chromatography coupled to electrochemical detection and...
متن کاملCannabinoid receptors are coupled to nitric oxide release in invertebrate immunocytes, microglia, and human monocytes.
The present study demonstrates that stereoselective binding sites for anandamide, a naturally occurring cannabinoid substance, can be found in invertebrate immunocytes and microglia. The anandamide-binding site is monophasic and of high affinity, exhibiting a Kd of 34.3 nM with a Bmax of 441 fmol/mg protein. These sites are highly selective, as demonstrated by the inability of other types of si...
متن کاملA 3D User Interface for Visualizing Neuron Location in Invertebrate Ganglia
Invertebrate nervous systems serve as important models for neuroscience research because they are comprised of relatively small numbers of individually identified neurons. There is no universal means of documenting locations of individual neurons that allows variability between specimens and can be generalized to different species. We present a new technique for visualizing and documenting neur...
متن کاملIba1 expressing microglia in the dorsal root ganglia become activated following peripheral nerve injury in rats.
The presence of microglia in dorsal root ganglia (DRG) has not been reported earlier. The dorsal root ganglia contain satellite glial cells (SGCs) and macrophages, which are considered to have infiltrated from the systemic blood. An attempt was made to investigate whether microglia as found in the central nervous system are also present in the dorsal root ganglia of untreated rats and following...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1994
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.91.19.9180